Contribution of the B oligomer to the protective activity of genetically attenuated pertussis toxin.
An enzymatically deficient recombinant S1 subunit, in which Arg-9 was replaced by Lys, was combined with native B oligomer to form a mutant holotoxin molecule. This molecule exhibited decreased leukocytosis-promoting and histamine-sensitizing activities compared with those of the native toxin, suppo...
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| Yayımlandı: | Infect Immun |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1991
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258899/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1894354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.59.10.3407-3410.1991 |
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