Effect of mutations in lipooligosaccharide biosynthesis genes on virulence of Haemophilus influenzae type b.

Chemical mutagenesis techniques and genetic transformation methods were used to construct isogenic mutants of Haemophilus influenzae type b (Hib) defective in the ability to synthesize lipooligosaccharide (LOS). A mutant (17B) which expressed a LOS molecule with an altered oligosaccharide was less v...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Cope, L D, Yogev, R, Mertsola, J, Argyle, J C, McCracken, G H, Hansen, E J
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1990
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1694825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.7.2343-2351.1990
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