Effect of mutations in lipooligosaccharide biosynthesis genes on virulence of Haemophilus influenzae type b.

Chemical mutagenesis techniques and genetic transformation methods were used to construct isogenic mutants of Haemophilus influenzae type b (Hib) defective in the ability to synthesize lipooligosaccharide (LOS). A mutant (17B) which expressed a LOS molecule with an altered oligosaccharide was less v...

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Argitaratua izan da:	Infect Immun
Egile Nagusiak:	Cope, L D, Yogev, R, Mertsola, J, Argyle, J C, McCracken, G H, Hansen, E J
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 1990
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC258818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1694825/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.7.2343-2351.1990
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