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The nature of the lymphopenic environment dictates protective function of homeostatic-memory CD8(+) T cells

A functional memory T cell pool is critical for resistance to pathogen reinfection. Lymphopenia produces memory-like CD8(+) T cells through homeostatic proliferation, and such “HP-memory” cells can control lethal bacterial infections similarly to conventional, antigen-experienced, memory T cells. Th...

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Detaylı Bibliyografya
Asıl Yazarlar: Hamilton, Sara E., Jameson, Stephen C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587628/
https://ncbi.nlm.nih.gov/pubmed/19020089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806487105
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