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The nature of the lymphopenic environment dictates protective function of homeostatic-memory CD8(+) T cells
A functional memory T cell pool is critical for resistance to pathogen reinfection. Lymphopenia produces memory-like CD8(+) T cells through homeostatic proliferation, and such “HP-memory” cells can control lethal bacterial infections similarly to conventional, antigen-experienced, memory T cells. Th...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587628/ https://ncbi.nlm.nih.gov/pubmed/19020089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806487105 |
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