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Phage φ29 and Nf terminal protein-priming domain specifies the internal template nucleotide to initiate DNA replication

Bacteriophages φ29 and Nf from Bacillus subtilis start replication of their linear genome at both DNA ends by a protein-primed mechanism, by which the DNA polymerase, in a template-instructed reaction, adds 5′-dAMP to a molecule of terminal protein (TP) to form the initiation product TP-dAMP. Mutati...

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Detalles Bibliográficos
Main Authors: Longás, Elisa, Villar, Laurentino, Lázaro, José M., de Vega, Miguel, Salas, Margarita
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587616/
https://ncbi.nlm.nih.gov/pubmed/19011105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809882105
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