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Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology
Motor learning and neuro-adaptations to drugs of abuse rely upon neuronal signaling in the striatum. Cyclin-dependent kinase 5 (Cdk5) regulates striatal dopamine neurotransmission and behavioral responses to cocaine. Although the role for Cdk5 in neurodegeneration in the cortex and hippocampus and i...
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Auteurs principaux: | , , , , , , , , , , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
National Academy of Sciences
2008
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587606/ https://ncbi.nlm.nih.gov/pubmed/19017804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806078105 |
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