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Revisiting the mechanism of macrolide-antibiotic resistance mediated by ribosomal protein L22
Bacterial antibiotic resistance can occur by many mechanisms. An intriguing class of mutants is resistant to macrolide antibiotics even though these drugs still bind to their targets. For example, a 3-residue deletion (ΔMKR) in ribosomal protein L22 distorts a loop that forms a constriction in the r...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587587/ https://ncbi.nlm.nih.gov/pubmed/19015512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810357105 |
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