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NMDA-induced Seizure Intensity is Enhanced in COX-2 Deficient Mice

Pharmacological inhibition or genetic deletion of cyclooxygenase (COX)-2, but not COX-1, has been shown to increase susceptibility to kainic acid (KA)-induced excitotoxicity. However, it is unclear if susceptibility to excitotoxins that act through other neurotransmitter receptors is altered by COX-...

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Detalhes bibliográficos
Main Authors: Toscano, Christopher D., Kingsley, Philip J., Marnett, Lawrence J., Bosetti, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587528/
https://ncbi.nlm.nih.gov/pubmed/18834901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2008.08.008
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