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Altered GABAergic Neurotransmission is Associated with Increased Kainate-Induced Seizure in Prostaglandin-Endoperoxide Synthase-2 Deficient Mice

Excitotoxicity involves over activation of brain excitatory glutamate receptors and has been implicated in neurological, neurodegenerative and neuropsychiatric diseases. Metabolism of arachidonic acid (AA) through the phospholipase A(2) (PLA(2))/ prostaglandin-endoperoxide synthase (PTGS) pathway is...

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Detalhes bibliográficos
Main Authors: Toscano, Christopher D., Ueda, Yumi, Tomita, York A., Vicini, Stefano, Bosetti, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423277/
https://ncbi.nlm.nih.gov/pubmed/18355636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2007.10.004
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