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Altered GABAergic Neurotransmission is Associated with Increased Kainate-Induced Seizure in Prostaglandin-Endoperoxide Synthase-2 Deficient Mice

Excitotoxicity involves over activation of brain excitatory glutamate receptors and has been implicated in neurological, neurodegenerative and neuropsychiatric diseases. Metabolism of arachidonic acid (AA) through the phospholipase A(2) (PLA(2))/ prostaglandin-endoperoxide synthase (PTGS) pathway is...

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Bibliographische Detailangaben
Hauptverfasser: Toscano, Christopher D., Ueda, Yumi, Tomita, York A., Vicini, Stefano, Bosetti, Francesca
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423277/
https://ncbi.nlm.nih.gov/pubmed/18355636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2007.10.004
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