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Pulsatile equibiaxial stretch inhibits thrombin-induced RhoA and NF-κB activation

This study investigated interactions between the effects of mechanical stretch and thrombin on RhoA activation in rat aortic smooth muscle cells (RASMC). Equibiaxial, pulsatile stretch or thrombin produced a significant increase in RhoA activation. Surprisingly, in combination, 30 minutes of stretch...

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Detalhes bibliográficos
Main Authors: Haga, Jason H., Kaunas, Roland, Radeff-Huang, Julie, Weems, Jessica M., Estrada, Kristine D., Chien, Shu, Brown, Joan Heller, Seasholtz, Tammy M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587448/
https://ncbi.nlm.nih.gov/pubmed/18474218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.05.013
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