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Efficient access to enantiomerically pure cyclic α-amino esters through a lipase-catalyzed kinetic resolution
A series of α-amino acid derivatives containing the 2,3-dihydroindole or octahydroindole core have been chemoenzymatically synthesized in good overall yields and high enantiomeric purity under mild reaction conditions using lipases for the introduction of chirality. Candida antarctica lipase type A...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587339/ https://ncbi.nlm.nih.gov/pubmed/20104250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetasy.2008.06.010 |
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