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Efficient access to enantiomerically pure cyclic α-amino esters through a lipase-catalyzed kinetic resolution

A series of α-amino acid derivatives containing the 2,3-dihydroindole or octahydroindole core have been chemoenzymatically synthesized in good overall yields and high enantiomeric purity under mild reaction conditions using lipases for the introduction of chirality. Candida antarctica lipase type A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alatorre-Santamaría, Sergio, Rodriguez-Mata, María, Gotor-Fernández, Vicente, de Mattos, Marcos Carlos, Sayago, Francisco J., Jiménez, Ana I., Cativiela, Carlos, Gotor, Vicente
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587339/
https://ncbi.nlm.nih.gov/pubmed/20104250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetasy.2008.06.010
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