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Lithocholic acid down-regulation of NF-κB activity through vitamin D receptor in colonic cancer cells
Lithocholic acid (LCA), a secondary bile acid, is a vitamin D receptor (VDR) ligand. 1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), the hormonal form of vitamin D, is involved in the anti-inflammatory action through VDR. Therefore, we hypothesize that LCA acts like 1,25(OH)(2)D(3) to drive anti-infla...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587242/ https://ncbi.nlm.nih.gov/pubmed/18515093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2008.01.003 |
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