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Both IKK-α and IKK-β are implicated in the arsenite-induced AP-1 transactivation correlating with cell apoptosis through NF-κB activity-independent manner

Arsenite has been well-proved to act as both an environmental carcinogen as well as a tumor therapeutic agent. AP-1 is one of the transcription factors that can be induced upon arsenite stimulation. However, the study on the mechanism and the function of the arsenite-induced AP-1 transactivation rem...

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Main Authors: Song, Lun, Li, Jingxia, Hu, Meiru, Huang, Chuanshu
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587112/
https://ncbi.nlm.nih.gov/pubmed/18508047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.04.002
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