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Total Synthesis of (±)-Strychnine via a [4+2]-Cycloaddition/Rearrangement Cascade

A new strategy for the synthesis of the Strychnos alkaloid (±)-strychnine has been developed and is based on an intramolecular [4+2]-cycloaddition/rearrangement cascade of an indolyl substituted amidofuran. The critical D-ring was assembled by an intramolecular palladium catalyzed enolate-driven cro...

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Detalhes bibliográficos
Main Authors: Zhang, Hongjun, Boonsombat, Jutatip, Padwa, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587098/
https://ncbi.nlm.nih.gov/pubmed/17217284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol062728b
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