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Non-catalytic reaction of isonitriles and carboxylic acids en route to amide type linkages
This protocol describes the preparation of an N-methyl-asparagine linked glycosyl amino acid, based on a reaction between carboxylic acids and isonitriles. Under microwave/thermolysis, carboxylic acids can couple with isonitriles without external catalyst, to afford N-formyl-amides, which may be fur...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587016/ https://ncbi.nlm.nih.gov/pubmed/18833204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2008.153 |
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