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Addressing Mechanistic Issues in the Coupling of Isonitriles and Carboxylic Acids: Potential Routes to Peptidic Constructs

[Image: see text] Mechanistic issues surrounding the 2CC (two component coupling) reaction of carboxylic acids with isonitriles have been investigated. Experimental details suggest the FCMA (formimidate carboxylate mixed anhydride) intermediate exists in both interdictable and non-interdictable form...

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Detaylı Bibliyografya
Asıl Yazarlar: Li, Xuechen, Yuan, Yu, Kan, Cindy, Danishefsky, Samuel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580816/
https://ncbi.nlm.nih.gov/pubmed/18783225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja804709s
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