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On The Two Component Microwave Mediated Reaction of Isonitriles with Carboxylic Acids: Regarding Alleged Formimidate Carboxylate Mixed Anhydrides

[Image: see text] Microwave induced two component coupling (2CC) reaction of carboxylic acids with isonitriles gives rise to various N-formylamides. The formimidate carboxylate mixed anhydride (FCMA) is proposed as the reactive intermediate, which undergoes 1,3-O → N acyl transfer to give the observ...

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Autori principali: Li, Xuechen, Yuan, Yu, Berkowitz, William F., Todaro, Louis J., Danishefsky, Samuel J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580818/
https://ncbi.nlm.nih.gov/pubmed/18783224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja8047078
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