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High Affinity Binding of (3)[H]-Cimetidine to a Heme-Containing Protein in Rat Brain

[(3)H]-Cimetidine (3HCIM) specifically binds to an unidentified site in the rat brain. Because recently-described ligands for this site have pharmacological activity, 3HCIM binding was presently characterized. 3HCIM binding was saturable, heat-labile, and distinct from the histamine H(2) receptor. T...

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Autors principals: Stadel, Rebecca, Yang, Jun, Nalwalk, Julia W., Phillips, James G., Hough, Lindsay B.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586985/
https://ncbi.nlm.nih.gov/pubmed/18094038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.107.017889
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