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Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding.

[3H]Diazepam appears to bind specifically to a single, saturable, binding site located on rat brain membranes, with an affinity constant near 3 nM at pH 7.4. Specific binding constitutes more than 90% of total binding at 0 degrees and less than 10% of total binding at 37 degrees. Arrhenius plots sug...

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Detalhes bibliográficos
Main Authors: Braestrup, C, Squires, R F
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431738/
https://ncbi.nlm.nih.gov/pubmed/20632
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