Murine ES-derived pancreatic acinar cells recapitulate features of early pancreatic differentiation

BACKGROUND & AIMS: Acinar cells constitute 90% of the pancreas epithelium, are polarized, and secrete digestive enzymes. These cells play a crucial role in pancreatitis and pancreatic cancer. However, there are no models to study normal acinar cell differentiation in vitro. The aim of this work...

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Detalhes bibliográficos
Main Authors: Rovira, Meritxell, Delaspre, Fabien, Massumi, Mohammad, Serra, Selma A., Valverde, Miguel Angel, Lloreta, Josep, Dufresne, Marlène, Payré, Bruno, Konieczny, Stephen F., Savatier, Pierre, Real, Francisco X., Skoudy, Anouchka
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586982/
https://ncbi.nlm.nih.gov/pubmed/18725222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.06.049
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