Transforming growth factor (TGF)beta, fibroblast growth factor (FGF) and retinoid signalling pathways promote pancreatic exocrine gene expression in mouse embryonic stem cells.

Extracellular signalling cues play a major role in the activation of differentiation programmes. Mouse embryonic stem (ES) cells are pluripotent and can differentiate into a wide variety of specialized cells. Recently, protocols designed to induce endocrine pancreatic differentiation in vitro have b...

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Bibliografische gegevens
Hoofdauteurs: Skoudy, Anouchka, Rovira, Meritxell, Savatier, Pierre, Martin, Franz, León-Quinto, Trinidad, Soria, Bernat, Real, Francisco X
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2004
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224110/
https://ncbi.nlm.nih.gov/pubmed/14733613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20031784
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