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hMena(+11a) Isoform Serves as a Marker of Epithelial Phenotype and Sensitivity to EGFR Inhibition in Human Pancreatic Cancer Cell Lines

PURPOSE: hMena, member of the Ena/VASP protein family, is a cytoskeletal protein that is involved in the regulation of cell motility and adhesion. The aim of this study was to determine whether or not the expression of hMena isoforms correlated with sensitivity to EGFR tyrosine kinase inhibitors and...

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Main Authors: Pino, Maria S., Balsamo, Michele, Di Modugno, Francesca, Mottolese, Marcella, Alessio, Massimo, Melucci, Elisa, Milella, Michele, McConkey, David J., Philippar, Ulrike, Gertler, Frank B., Natali, Pier Giorgio, Nistico, Paola
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586967/
https://ncbi.nlm.nih.gov/pubmed/18676769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0436
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