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hMena(+11a) Isoform Serves as a Marker of Epithelial Phenotype and Sensitivity to EGFR Inhibition in Human Pancreatic Cancer Cell Lines

PURPOSE: hMena, member of the Ena/VASP protein family, is a cytoskeletal protein that is involved in the regulation of cell motility and adhesion. The aim of this study was to determine whether or not the expression of hMena isoforms correlated with sensitivity to EGFR tyrosine kinase inhibitors and...

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Bibliografski detalji
Glavni autori: Pino, Maria S., Balsamo, Michele, Di Modugno, Francesca, Mottolese, Marcella, Alessio, Massimo, Melucci, Elisa, Milella, Michele, McConkey, David J., Philippar, Ulrike, Gertler, Frank B., Natali, Pier Giorgio, Nistico, Paola
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586967/
https://ncbi.nlm.nih.gov/pubmed/18676769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0436
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