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A reducing environment stabilizes HIF-2α in SH-SY5Y cells under hypoxic conditions

Accumulating evidence suggests that hypoxia-inducible factor-2 (HIF-2) is important for the cellular response to hypoxia. However, it is not clear how HIF-2 is regulated under hypoxic conditions. We investigated kinetic changes in redox status and HIF-2α accumulation in hypoxic SH-SY5Y cells. Our re...

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Bibliografske podrobnosti
Main Authors: Chen, Hu, Shi, Honglian
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586911/
https://ncbi.nlm.nih.gov/pubmed/18957292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.10.031
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