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Catalytic mechanism of human DNA polymerase λ with Mg(2+) and Mn(2+) from ab initio quantum mechanical/molecular mechanical studies
DNA polymerases play a crucial role in the cell cycle due to their involvement in genome replication and repair. Understanding the reaction mechanism by which these polymerases carry out their function can provide insights into these processes. Recently, the crystal structures of human DNA polymeras...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586819/ https://ncbi.nlm.nih.gov/pubmed/18692600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.07.007 |
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