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Combining Bevacizumab with Temozolomide Increases the Antitumor Efficacy of Temozolomide in a Human Glioblastoma Orthotopic Xenograft Model

PURPOSE: The aims of the present work were to investigate the in vitro and in vivo antiangiogenic effects of chronic temozolomide treatment on various glioma models and to demonstrate whether bevacizumab (Avastin) increased the therapeutic benefits contributed by temozolomide in glioma. EXPERIMENTAL...

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Main Authors: Mathieu, Véronique, De Nève, Nancy, Le Mercier, Marie, Dewelle, Janique, Gaussin, Jean-François, Dehoux, Mischael, Kiss, Robert, Lefranc, Florence
Format: Artigo
Jezik:Inglês
Izdano: Neoplasia Press Inc. 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586689/
https://ncbi.nlm.nih.gov/pubmed/19048117
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