Combining Bevacizumab with Temozolomide Increases the Antitumor Efficacy of Temozolomide in a Human Glioblastoma Orthotopic Xenograft Model

PURPOSE: The aims of the present work were to investigate the in vitro and in vivo antiangiogenic effects of chronic temozolomide treatment on various glioma models and to demonstrate whether bevacizumab (Avastin) increased the therapeutic benefits contributed by temozolomide in glioma. EXPERIMENTAL...

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Main Authors: Mathieu, Véronique, De Nève, Nancy, Le Mercier, Marie, Dewelle, Janique, Gaussin, Jean-François, Dehoux, Mischael, Kiss, Robert, Lefranc, Florence
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2008
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586689/
https://ncbi.nlm.nih.gov/pubmed/19048117
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