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TDP-43 accumulation in IBM muscle suggests a common pathogenic mechanism with Frontotemporal dementia
TDP-43 is found in ubiquitinated inclusions (UBIs) in some frontotemporal dementias (FTD-U). One form of FTD-U, due to mutations in VCP, occurs with an inclusion body myopathy (IBMPFD). Since IBMPFD brain has TDP-43 in UBIs, we looked for TDP-43 inclusions in IBMPFD muscle. In normal muscle TDP-43 i...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586594/ https://ncbi.nlm.nih.gov/pubmed/18796596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.2007.131334 |
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