Contact Guidance Mediated Three-Dimensional Cell Migration is Regulated by Rho/ROCK-Dependent Matrix Reorganization

Cells generate mechanical force to organize the extracellular matrix (ECM) and drive important developmental and reparative processes. Likewise, tumor cells invading into three-dimensional (3D) matrices remodel the ECM microenvironment. Importantly, we previously reported a distinct radial reorganiz...

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Detalhes bibliográficos
Main Authors: Provenzano, Paolo P., Inman, David R., Eliceiri, Kevin W., Trier, Steven M., Keely, Patricia J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Spectroscopy, Imaging, Other Techniques
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586586/
https://ncbi.nlm.nih.gov/pubmed/18775961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.133116
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