Llwytho...
Bupivacaine Blocks N-Type Inactivating K(v) Channels in the Open State: No Allosteric Effect on Inactivation Kinetics
Local anesthetics bind to ion channels in a state-dependent manner. For noninactivating voltage-gated K channels the binding mainly occurs in the open state, while for voltage-gated inactivating Na channels it is assumed to occur mainly in inactivated states, leading to an allosterically caused incr...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The Biophysical Society
2008
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586568/ https://ncbi.nlm.nih.gov/pubmed/18790854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130518 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|