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Analysis of Molecular Concentration and Brightness from Fluorescence Fluctuation Data with an Electron Multiplied CCD Camera

We demonstrate the calculation of particle brightness and concentration from fluorescence-fluctuation photon-counting statistics using an electron-multiplied charge-coupled device (EMCCD) camera. This technique provides a concentration-independent measure of particle brightness in dynamic systems. T...

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Detalhes bibliográficos
Main Authors: Unruh, Jay R., Gratton, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586556/
https://ncbi.nlm.nih.gov/pubmed/18805922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.130310
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