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Mapping the Number of Molecules and Brightness in the Laser Scanning Microscope

We describe a technique based on moment-analysis for the measurement of the average number of molecules and brightness in each pixel in fluorescence microscopy images. The average brightness of the particle is obtained from the ratio of the variance to the average intensity at each pixel. To obtain...

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Autors principals: Digman, Michelle A., Dalal, Rooshin, Horwitz, Alan F., Gratton, Enrico
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257897/
https://ncbi.nlm.nih.gov/pubmed/18096627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114645
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