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Mapping the Number of Molecules and Brightness in the Laser Scanning Microscope

We describe a technique based on moment-analysis for the measurement of the average number of molecules and brightness in each pixel in fluorescence microscopy images. The average brightness of the particle is obtained from the ratio of the variance to the average intensity at each pixel. To obtain...

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Detalhes bibliográficos
Main Authors: Digman, Michelle A., Dalal, Rooshin, Horwitz, Alan F., Gratton, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2257897/
https://ncbi.nlm.nih.gov/pubmed/18096627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.114645
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