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Receptor Tyrosine Phosphatase β (RPTPβ) Activity and Signaling Are Attenuated by Glycosylation and Subsequent Cell Surface Galectin-1 Binding

O-Mannosyl-linked glycosylation is abundant within the central nervous system, yet very few glycoproteins with this glycan modification have been identified. Congenital diseases with significant neurological defects arise from inactivating mutations found within the glycosyltransferases that act ear...

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Autors principals: Abbott, Karen L., Matthews, Russell T., Pierce, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586282/
https://ncbi.nlm.nih.gov/pubmed/18838383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803646200
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