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Receptor Tyrosine Phosphatase β (RPTPβ) Activity and Signaling Are Attenuated by Glycosylation and Subsequent Cell Surface Galectin-1 Binding

O-Mannosyl-linked glycosylation is abundant within the central nervous system, yet very few glycoproteins with this glycan modification have been identified. Congenital diseases with significant neurological defects arise from inactivating mutations found within the glycosyltransferases that act ear...

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Detalhes bibliográficos
Main Authors: Abbott, Karen L., Matthews, Russell T., Pierce, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586282/
https://ncbi.nlm.nih.gov/pubmed/18838383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803646200
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