Ricin B Chain Targeted to the Endoplasmic Reticulum of Tobacco Protoplasts Is Degraded by a CDC48- and Vacuole-independent Mechanism

The B chain of ricin was expressed and delivered to the endoplasmic reticulum of tobacco protoplasts where it disappeared with time in a manner consistent with degradation. This turnover did not occur in the vacuoles or upon secretion. Indeed, several lines of evidence indicate that, in contrast to...

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Main Authors: Chamberlain, Kerry L., Marshall, Richard S., Jolliffe, Nicholas A., Frigerio, Lorenzo, Ceriotti, Aldo, Lord, J. Michael, Roberts, Lynne M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Protein Synthesis, Post-Translational Modification, and Degradation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586253/
https://ncbi.nlm.nih.gov/pubmed/18832379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805222200
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