Frameshift mutations in coding repeats of protein tyrosine phosphatase genes in colorectal tumors with microsatellite instability

BACKGROUND: Protein tyrosine phosphatases (PTPs) like their antagonizing protein tyrosine kinases are key regulators of signal transduction thereby assuring normal control of cellular growth and differentiation. Increasing evidence suggests that mutations in PTP genes are associated with human malig...

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Hlavní autoři: Korff, Sebastian, Woerner, Stefan M, Yuan, Yan P, Bork, Peer, von Knebel Doeberitz, Magnus, Gebert, Johannes
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586028/
https://ncbi.nlm.nih.gov/pubmed/19000305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-329
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