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Frameshift mutations in coding repeats of protein tyrosine phosphatase genes in colorectal tumors with microsatellite instability

BACKGROUND: Protein tyrosine phosphatases (PTPs) like their antagonizing protein tyrosine kinases are key regulators of signal transduction thereby assuring normal control of cellular growth and differentiation. Increasing evidence suggests that mutations in PTP genes are associated with human malig...

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Detaylı Bibliyografya
Asıl Yazarlar: Korff, Sebastian, Woerner, Stefan M, Yuan, Yan P, Bork, Peer, von Knebel Doeberitz, Magnus, Gebert, Johannes
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586028/
https://ncbi.nlm.nih.gov/pubmed/19000305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-329
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