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Frameshift mutations in coding repeats of protein tyrosine phosphatase genes in colorectal tumors with microsatellite instability

BACKGROUND: Protein tyrosine phosphatases (PTPs) like their antagonizing protein tyrosine kinases are key regulators of signal transduction thereby assuring normal control of cellular growth and differentiation. Increasing evidence suggests that mutations in PTP genes are associated with human malig...

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Detalhes bibliográficos
Main Authors: Korff, Sebastian, Woerner, Stefan M, Yuan, Yan P, Bork, Peer, von Knebel Doeberitz, Magnus, Gebert, Johannes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586028/
https://ncbi.nlm.nih.gov/pubmed/19000305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-329
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