Effects of Naturally Occurring Coumarins on Hepatic Drug Metabolizing Enzymes in Mice

Cytochromes P450 (P450s) and glutathione S-transferases (GSTs) constitute two important enzyme families involved in carcinogen metabolism. Generally, P450s play activation or detoxifying roles while GSTs act primarily as detoxifying enzymes. We previously demonstrated that oral administration of the...

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Bibliografiset tiedot
Päätekijät: Kleiner, Heather E., Xia, Xiojun, Sonoda, Junichiro, Zhang, Jun, Pontius, Elizabeth, Abey, Jane, Evans, Ronald M., Moore, David D., DiGiovanni., John
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585982/
https://ncbi.nlm.nih.gov/pubmed/18692084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.07.004
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