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COMPARISON OF CITRUS COUMARINS ON CARCINOGEN-DETOXIFYING ENZYMES IN NRF2 KNOCKOUT MICE
Naturally occurring coumarins possess anti-carcinogenic activities in part by inducing carcinogen-detoxifying enzymes glutathione S-transferase (GST) and/or NAD(P)H quinone oxidoreductase (NQO1). Our goal was to determine whether citrus coumarins induce hepatic GST and/or NQO1 via activation of Nrf2...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676710/ https://ncbi.nlm.nih.gov/pubmed/19150646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2008.12.014 |
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