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Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene

BACKGROUND: Activation of nuclear factor erythroid 2-related factor (Nrf2), which belongs to the basic leucine zipper transcription factor family, is a strategy for cancer chemopreventive phytochemicals. It is an important regulator of genes induced by oxidative stress, such as glutathione S-transfe...

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Main Authors: Becks, Lisa, Prince, Misty, Burson, Hannah, Christophe, Christopher, Broadway, Mason, Itoh, Ken, Yamamoto, Masayuki, Mathis, Michael, Orchard, Elysse, Shi, Runhua, McLarty, Jerry, Pruitt, Kevin, Zhang, Songlin, Kleiner-Hancock, Heather E
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964634/
https://ncbi.nlm.nih.gov/pubmed/20932318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-540
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