Effects of Naturally Occurring Coumarins on Hepatic Drug Metabolizing Enzymes in Mice

Cytochromes P450 (P450s) and glutathione S-transferases (GSTs) constitute two important enzyme families involved in carcinogen metabolism. Generally, P450s play activation or detoxifying roles while GSTs act primarily as detoxifying enzymes. We previously demonstrated that oral administration of the...

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Detalhes bibliográficos
Main Authors: Kleiner, Heather E., Xia, Xiojun, Sonoda, Junichiro, Zhang, Jun, Pontius, Elizabeth, Abey, Jane, Evans, Ronald M., Moore, David D., DiGiovanni., John
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585982/
https://ncbi.nlm.nih.gov/pubmed/18692084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.07.004
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