Effects of Naturally Occurring Coumarins on Hepatic Drug Metabolizing Enzymes in Mice

Cytochromes P450 (P450s) and glutathione S-transferases (GSTs) constitute two important enzyme families involved in carcinogen metabolism. Generally, P450s play activation or detoxifying roles while GSTs act primarily as detoxifying enzymes. We previously demonstrated that oral administration of the...

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書誌詳細
主要な著者: Kleiner, Heather E., Xia, Xiojun, Sonoda, Junichiro, Zhang, Jun, Pontius, Elizabeth, Abey, Jane, Evans, Ronald M., Moore, David D., DiGiovanni., John
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585982/
https://ncbi.nlm.nih.gov/pubmed/18692084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.07.004
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