Effects of Naturally Occurring Coumarins on Hepatic Drug Metabolizing Enzymes in Mice

Cytochromes P450 (P450s) and glutathione S-transferases (GSTs) constitute two important enzyme families involved in carcinogen metabolism. Generally, P450s play activation or detoxifying roles while GSTs act primarily as detoxifying enzymes. We previously demonstrated that oral administration of the...

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Autores principales: Kleiner, Heather E., Xia, Xiojun, Sonoda, Junichiro, Zhang, Jun, Pontius, Elizabeth, Abey, Jane, Evans, Ronald M., Moore, David D., DiGiovanni., John
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585982/
https://ncbi.nlm.nih.gov/pubmed/18692084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2008.07.004
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