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Modulation of the Local SR Ca(2+) Release by Intracellular Mg(2+) in Cardiac Myocytes

In cardiac muscle, Ca(2+)-induced Ca(2+) release (CICR) from the sarcoplasmic reticulum (SR) defines the amplitude and time course of the Ca(2+) transient. The global elevation of the intracellular Ca(2+) concentration arises from the spatial and temporal summation of elementary Ca(2+) release event...

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Bibliographic Details
Main Authors: Gusev, Konstantin, Niggli, Ernst
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585859/
https://ncbi.nlm.nih.gov/pubmed/19029377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810119
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