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Lipid mediators in innate immunity against tuberculosis: opposing roles of PGE(2) and LXA(4) in the induction of macrophage death
Virulent Mycobacterium tuberculosis (Mtb) induces a maladaptive cytolytic death modality, necrosis, which is advantageous for the pathogen. We report that necrosis of macrophages infected with the virulent Mtb strains H37Rv and Erdmann depends on predominant LXA(4) production that is part of the ant...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585850/ https://ncbi.nlm.nih.gov/pubmed/18955568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080767 |
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