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Evasion of innate immunity by Mycobacterium tuberculosis: is death an exit strategy?
Virulent Mycobacterium tuberculosis inhibits apoptosis and triggers necrosis of host macrophages to evade innate immunity and delay the initiation of adaptive immunity. By contrast, attenuated M. tuberculosis induces macrophage apoptosis, an innate defence mechanism that reduces bacterial viability....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221965/ https://ncbi.nlm.nih.gov/pubmed/20676146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro2387 |
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