Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii

Tpl2 (Tumor progression locus 2), also known as Cot/MAP3K8, is a hematopoietically expressed serine-threonine kinase. Tpl2 is known to have critical functions in innate immunity in regulating tumor necrosis factor–α, Toll-like receptor, and G protein–coupled receptor signaling; however, our understa...

Full description

Saved in:
Bibliographic Details
Main Authors: Watford, Wendy T., Hissong, Bruce D., Durant, Lydia R., Yamane, Hidehiro, Muul, Linda M., Kanno, Yuka, Tato, Cristina M., Ramos, Haydeé L., Berger, Alan E., Mielke, Lisa, Pesu, Marko, Solomon, Benjamin, Frucht, David M., Paul, William E., Sher, Alan, Jankovic, Dragana, Tsichlis, Philip N., O'Shea, John J.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585846/
https://ncbi.nlm.nih.gov/pubmed/19001140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081461
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items