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Proprotein convertase FURIN constrains Th2 differentiation and is critical for host resistance against Toxoplasma gondii
The proprotein convertase subtilisin/kexin (PCSK) enzymes proteolytically convert immature proproteins into bioactive molecules and thereby they serve as key regulators of cellular homeostasis. The archetype PCSK, FURIN is a direct target gene of the IL-12/STAT4 pathway and it is upregulated in T he...
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| 發表在: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4261955/ https://ncbi.nlm.nih.gov/pubmed/25355923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401629 |
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