A novel genetic strategy reveals unexpected roles of the Swi–Snf–like chromatin-remodeling BAF complex in thymocyte development

We have developed a general strategy for creating littermates bearing either a tissue-specific point mutation or deletion in any target gene, and used the method to dissect the roles of Brg, the ATPase subunit of the chromatin-remodeling Brg-associated factor (BAF) complex, in early thymocyte develo...

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Main Authors: Jani, Anant, Wan, Mimi, Zhang, Jianmin, Cui, Kairong, Wu, Jie, Preston-Hurlburt, Paula, Khatri, Rohini, Zhao, Keji, Chi, Tian
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2008
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585832/
https://ncbi.nlm.nih.gov/pubmed/18955569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080938
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