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Molecular basis of CD4 repression by the Swi/Snf-like BAF chromatin remodeling complex
The BAF chromatin remodeling complex directly binds the CD4 silencer and is essential for CD4 repression during T cell development, because deletion of the ATPase subunit Brg1 or a dominant negative mutant of BAF57 each impairs CD4 repression in early thymocytes. Paradoxically, BAF57 is dispensable...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774848/ https://ncbi.nlm.nih.gov/pubmed/19180471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838909 |
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