Molecular basis of CD4 repression by the Swi/Snf-like BAF chromatin remodeling complex

The BAF chromatin remodeling complex directly binds the CD4 silencer and is essential for CD4 repression during T cell development, because deletion of the ATPase subunit Brg1 or a dominant negative mutant of BAF57 each impairs CD4 repression in early thymocytes. Paradoxically, BAF57 is dispensable...

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Bibliografiske detaljer
Main Authors: Wan, Mimi, Zhang, Jianmin, Lai, Dazhi, Jani, Anant, Prestone-Hurlburt, Paula, Ramachandran, Aruna, Schnitzler, Gavin R., Chi, Tian
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774848/
https://ncbi.nlm.nih.gov/pubmed/19180471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838909
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